Opioids act on the brain and body by attaching to specific proteins called
Opioid receptors, which are found in the brain, spinal cord, and
gastrointestinal tract. When these drugs attach to certain opioid receptors,
they can block the perception of pain. Opioids can produce drowsiness, nausea,
constipation, and, depending upon the amount of Drug taken, depress
respiration. Opioid drugs also can induce euphoria by affecting the brain
regions that mediate what we perceive as pleasure. This feeling is often
intensified for those who abuse opioids when administered by routes other than
those recommended. For example, OxyContin often is snorted or injected to enhance
its euphoric effects, while at the same time increasing the risk for serious
medical consequences, such as opioid Overdose.
What are the possible consequences
of opioid use and abuse?
Taken as directed, opioids can be
used to manage pain effectively. Many studies have shown that the properly
managed, short-term medical use of opioid Analgesic drugs is safe and rarely
causes Addiction-efined as the compulsive and uncontrollable use of drugs
despite adverse consequences-or dependence, which occurs when the body adapts
to the presence of a drug, and often results in Withdrawal symptoms when that
drug is reduced or stopped. Withdrawal symptoms include restlessness, muscle
and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps
("cold turkey"), and involuntary leg movements. Long-term use of
opioids can lead to Physical dependence and addiction. Taking a large single
dose of an opioid could cause severe respiratory depression that can lead to
death.
Is it safe to use opioid drugs with other medications?
Only under a physician's supervision can
opioids be used safely with other drugs. Typically, they should not be used
with other substances that depress the CNS, such as Alcohol, antihistamines,
Barbiturates, Benzodiazepines, or general anesthetics, because these
combinations increase the risk of life-threatening respiratory depression.
Strong physiological, emotional and/or psychological dependence on a substance such as alcohol or drugs that has progressed beyond voluntary control. For more on addiction see the section Addiction Information in this website.
Alcohol
Refers to ethyl alcohol or ethanol.
Analgesic
A group of medications that reduce pain.
Barbiturates
Depressant drugs that produce relaxation and sleep. Barbiturates include sleeping pills such as pentobarbital (Nembutal)and secobarbital (Seconal).
Benzodiazepines
A class of drugs used in medicine as minor tranquilizers which is frequently prescribed to treat anxiety. They are central nervous system depressants and are subject to abuse.
CNS
Central Nervous System
Drug
Any substance, other than food, that changes the function or structure of the body or mind when ingested. Drugs essentially are poisons. The degree they are taken determines the effect. A small amount acts as a stimulant. A greater amount acts as a sedative. A larger amount acts as a poison and can kill one dead. This is true of any drug. Each has a different amount at which it gives those results.
Drug abuse
The use of illegal drugs or the inappropriate use of legal drugs. The repeated use of drugs to produce pleasure, to alleviate stress, or to alter or avoid reality - or all three.
Opioid
Any chemical that has opiate-like effects; commonly used to refer to neurochemicals that activate opiate receptors (see Opiate Receptors).
Overdose
The condition that results when too much of a drug is taken, making a person sick or unconscious and sometimes resulting in death.
Physical dependence
An adaptive physiological state that occurs with regular drug use and results in a withdrawal syndrome when drug use is stopped; usually occurs with tolerance.
Withdrawal
Symptoms that occur after chronic use of a drug is reduced or stopped.
Drug Info 
Opioids act on the brain and body by attaching to specific proteins called
